Optimization of the Electric Field Distribution induced in the Brain during Transcranial Magnetic Stimulation (TMS) using the Continuum Design Sensitivity Analysis (CDSA)

نویسندگان

  • DONG-HUN KIM
  • G. E. GEORGHIOU
  • JONG-WOO CHOI
  • WON-EEL YUN
چکیده

Results are presented on the optimization of the electric field distribution obtained during Transcranial Magnetic Stimulation (TMS) for deep neuron stimulation by using the Continuum Design Sensitivity Analysis (CDSA) combined with a commercially available generalized finite element code (OPERA). In order to obtain a magnetic field that can penetrate deeply and safely to activate the brain’s central structures, an iron core is introduced and its shape is optimized, as opposed to searching for a combination of several coils that make both the analysis and construction of such a design very complex. It is revealed that the introduction of an optimized iron core enhances the magnitude and localization of the electric field induced inside the brain when compared with conventional coil structures. Key-Words: Design sensitivity analysis, Field localization, Finite element method, Induced electric field, Transcranial magnetic stimulation.

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تاریخ انتشار 1999